Clin Shoulder Elbow Search


Clin Shoulder Elbow > Volume 20(1); 2017 > Article
Clinics in Shoulder and Elbow 2017;20(1):3-9.
DOI:    Published online March 31, 2017.
Effectiveness of the Anti-adhesive Agent Protescal after Arthroscopic Rotator Cuff Repair: A Retrospective Study
Pill Ku Chung, Jae Chul Yoo, Jeung Yeol Jeong
Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Received: 9 July 2016   • Revised: 17 September 2016   • Accepted: 18 September 2016
BACKGROUND: Many hyaluronic acid (HA)-based anti-adhesive agents have been commercialized for clinical use in the pharmaceutical market. But their efficacy in arthroscopic rotator cuff repairs remains elusive. To determine their efficacy, we performed a comparative analysis of the effects of two hyaluronate/carboxymethylcellulose (CMC)-based anti-adhesive agents, Protescal and Guardix.
We recruited a total of 256 patients who had received an arthroscopic rotator cuff repair at our hospital between January 2014 and March 2015. Among them, 96 patients fulfilled the study's selection criteria and were enrolled as the final population sample. Thirty patients who had received a postoperative injection of Protescal were allocated into Group A. Another 30 patients who had received a postoperative injection of Guardix were allocated into Group B. As controls, 36 patients who did not receive any injection were allocated into Group C. The patients included in this study were aged between 19 and 75 years. For the clinical assessment, we measured the following clinical parameters?the visual analogue scale for pain (PVAS), the American Shoulder and Elbow Surgeons (ASES) score, and the constant score, as well as passive range of motions (ROMs)?at three time-points (preoperatively, 2-month postoperatively, and 6-month postoperatively).
We found that Group A compared to Group B tended to show a swifter recovery in passive anterior elevation and in internal rotation by the 2-month postoperative follow-up, but the differences were not statistically significant.
We found that the effects of HA/CMC-based injections were minimal after arthroscopic rotator cuff repairs.
Key Words: Rotator cuff tears; Anti-adhesive agents; Cuff healing rate


Browse all articles >

Editorial Office
#6603, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea
Tel: +82-2-3410-1854    Fax: +82-2-3410-0061    E-mail:                

Copyright © 2022 by Korean Shoulder and Elbow Society.

Developed in M2PI

Close layer
prev next